黄茹（博士），副教授，获华南师范大学生物物理学博士学位；2018.08~2021.06，在华南师范大学光学流动站做博士后；2021.07入职海南大学生物医学工程学院，加入光学免疫工程团队。
主要研究方向：
从事光学分子诊断技术在疾病早期诊断和监测的基础应用研究，主要研究方向有：
(1) 新型核酸扩增与光学检测平台技术的开发；
(2) 便携式核酸检测平台在癌症早期诊断与治疗监测方面的基础应用研究。
学术论文：
[1] Ting Zhou#, Ru Huang#,*, Mengqi Huang, Jinjin Shen, Yuanyue Shan, Da Xing*. CRISPR/Cas13a powered portable electrochemiluminescence chip for ultrasensitive and specific miRNA detection. Advanced Science 2020, 7(13), 1903661. （JCR工程技术一区，高被引）
[2] Ru Huang, Xiaoming Zhou*, Chunsun Zhang, Da Xing*. High-specific microRNA detection based on dual-recycling cascade reaction and nicking endonuclease signal amplification. Sensors and Actuators B: Chemical 2018, 264, 169-176. （JCR工程技术一区）
[3] Ru Huang, Yuhui Liao, Xiaoming Zhou*, Yu Fu, Da Xing*. Multiplexed detection of microRNA biomarkers from tumor cells and tissues with a homogeneous nano-photon switch. Sensors and Actuators B: Chemical 2017, 247, 505-513. （JCR工程技术一区）
[4] Ting Zhou, Mengqi Huang, Jinqiong Lin, Ru Huang*, Da Xing*. High-fidelity CRISPR/Cas13a trans-cleavage-triggered rolling circle amplified DNAzyme for visual profiling of microRNA. Analytical Chemistry 2021, 93, 4, 2038-2044. （JCR化学一区）
[5] Yong Sha, Ru Huang*, Mengqi Huang, Huahua Yue, Yuanyue Shan, Jiaming Hu, Da Xing*. Cascade CRISPR/cas enables amplification-free microRNA sensing with fM-sensitivity and single-base-specificity. Chemical Communications 2021, 57, 247-250. （JCR化学二区，高被引）
主持科研项目：
① 国家自然科学基金，地区项目，22364013，2024/01 至 2027/12，32万元，主持；
② 海南省重点研发项目，ZDYF2024SHFZ134，2024/01至2026/12，64万元，主持。
招生需求：
招收分子生物学、生物化学、生物物理学、生物医学工程及相关专业的研究生。
联系方式：huangru@hainanu.edu.cn
Ru Huang
Dr. Huang Ru is an Associate Professor at the College of Biomedical Engineering, Hainan University, primarily engaged in research in the field of in vitro diagnostic technologies. She has published 13 SCI papers in internationally renowned academic journals such as Advanced Science, Analytic Chemistry, and Sensors & Actuators B: Chemical. Her work has been supported by multiple grants, including the National Natural Science Foundation of China and the Hainan Provincial Key Area R&D Program, etc. She serves as a Director of the Hainan Biomedical Engineering Society, a Youth Editorial Board Member for the journal Extracellular Vesicles and Circulating Nucleic Acids (EVCNA), has been invited as a Guest Associate Editor for Frontiers in Bioengineering and Biotechnology, and regularly acts as a reviewer for Sensors and Actuators B: Chemical, Analytical Chemistry, etc.
Research Experience
From 2011 to 2018, she earned her Ph.D. in Biophysics from South China Normal University.
From 2018 to 2021, she conducted postdoctoral research in the Optical Mobile Station at South China Normal University.
Since 2021, she joined the College of Biomedical Engineering at Hainan University, becoming a member of the Photo-immuno-engineering team.
Primary Courses Taught
Introduction to Biology (Undergraduate)
Minimally Invasive and Non-invasive Diagnostic Technologies and Applications (Graduate)
Modern Biological Analysis and Detection Technologies (Graduate)
Primary Research Directions
Her research primarily focuses on the fundamental applications of optical molecular diagnostic technologies for early disease diagnosis and monitoring, including (1) the development of novel nucleic acid amplification and optical detection platform technologies, and (2) fundamental applied research on portable nucleic acid detection platforms for early cancer diagnosis and treatment monitoring.
Representative Publications
1. Ting Zhou, Ru Huang,* Mengqi Huang, Jinjin Shen, Yuanyue Shan, and Da Xing* CRISPR/Cas13a powered portable electrochemiluminescence chip for ultrasensitive and specific miRNA detection. Advanced Science 2020, 1903661.
2. Fang Liu, Taixue An, Chen Zhou, Weijie Chen, Ru Huang,*, Feifan Zhou* Amplification-free orthogonal CRISPR/Cas system for rapid discrimination of bacterial vs viral infection in febrile children. Sensors & Actuators: B. Chemical 418 (2024) 136319.
3. Ting Zhou, Mengqi Huang, Jinqiong Lin, Ru Huang,* and Da Xing* High-fidelity CRISPR/Cas13a trans-cleavage-triggered rolling circle amplified DNAzyme for visual profiling of microRNA. Analytical Chemistry. 2021, 93, 2038−2044.
4. Lingyi Wu, Ting Zhou, Ru Huang* A universal CRISPR/Cas9-based electrochemiluminescence probe for sensitive and single-base-specific DNA detection. Sensors & Actuators: B. Chemical. 2022, 357, 131411.
5. Yong Sha, Ru Huang,* Mengqi Huang, Huahua Yue, Yuanyue Shan, Jiaming Hu and Da Xing* Cascade CRISPR/cas enables amplification-free microRNA sensing with fM-sensitivity and single-base-specificity. 2021, 57, 247-250.
