王亚龙（博士），副教授，硕、博士生导师，海南省D类人才，朱明强教授团队（分子靶向成像团队）。
研究方向：
1) 聚集诱导发光（AIE）探针的设计与合成；
2) 生物样本标记与荧光成像；
3) 小动物活体成像/光动力治疗；
4) 抗菌敷料开发。
招生需求：
招收化学、材料、生物、计算化学及相关专业的学生
联系方式：ylwang@hainanu.edu.cn
代表论文：
1. Lu Zhang1,#, Yu-Jian Cai1, #, Quan Chen1, 2#,Xin-Zheng Liang1, Tian-Yi Qin1,*, Zhao-Hui Wang1,*, Ya-Long Wang1,* and Ming-Qiang Zhu1,3. From bio-interfacial association to sustained delivery: a lipophilicity-tuned aggregation-induced emission photosensitizer hydrogel for infected wound therapy. Journal of Colloid and Interface Science, 2027, 728, 141782
2. Caiqiang Liao, Xinfeng Du, Zhang Lin, Yuting Luo, Yangyang Yu, Zhaohui Wang, Jun Peng, Zhongyong Xu, Xianwen Liang, Zhilong Wu, Ya-Long Wang,* Tianyi Qin,* Bin Liu and Ming-Qiang Zhu. N-alkyl Extension in Ionic Molecular Rotors: Facile Tuning of Sensing Modes for Albumin-based Host-guest Fluorescent Sensors. Angewandte Chemie International Edition, 2026, e1330357
3. Yi Cai#, Cai-Yun Wang#, Min Dong#, Zhang Lin, Cai-Qiang Liao, Ze-Jun Li, Tian-Yi Qin*, Zhao-Hui Wang*, Ya-Long Wang*, Ming-Qiang Zhu. Rational design of a V-shaped DNA-targeted photosensitizer enables endogenous DNA damage-driven cGAS-STING activation and systemic antitumor immunity. Materials Today Bio, 2026, 38, 103290
4. Linhui Peng, Yuting Luo, Zhiqing Xun, Zhongyong Xu, Taoyuze Lv, Xinrong Du, Zhaohui Wang, Ya-Long Wang*, Tianyi Qin*, Bin Liu, Ming-Qiang Zhu. A ratiometric fluorescent probe with distinct response to Aflatoxin B1 and B2a: probe design, bioimaging, and quantification. Food Chemistry, 2026, 519, 149714
5. Zhenyu Zhang, Junxin Yi, Zhang Lin, Zhaohui Wang, Ya-Long Wang,* Xinfeng Du,* and Tianyi Qin *. Nonconjugated Alkyl Chains in Ionic Molecular Rotor Fluorophores: An Effective Modulating Moiety for Amyloid-β Probes. Analytical Chemistry, 2026, 98(30), 22088-22099
6. Ze-Jun Li,§ Zhen-Yu Zhang,§ Yao-Yuan Jiang, Yun-Miao Liu, Jian Wang, Ya-Long Wang* Tian-Yi Qin* and Ming-Qiang Zhu*. Construction of High-Performance Wash-Free Aβ Probes Based on Amino Group Optimization and Amphiphilic Molecular Engineering Strategies. Analytical Chemistry, 2025, 97 (34), 18479-18489
7. Jian Wang# , Quan Chen# , Zhang Lin# , Deteng Zhang, Lu Zhang, Tian-Yi Qin*, Zhao-Hui Wang*, Ya-Long Wang* and Ming-Qiang Zhu. Functionalized Nanohydrogel for Accelerated Skin Burn Repair with Photo-activated Bacteria Elimination and Pro-Regenerative Protein Loading. Chemical Engineering Journal, 2025, 522, 167777
8. Zhen-Yu Zhang#, Ze-Jun Li#, Ying-Hao Tang#, Ting-Ting Hou, Liang Xu, Zhao-Hui Wang, Tian-Yi Qin*, Ya-Long Wang*, Ming-Qiang Zhu. Tailoring near-infrared amyloid-β probes with high-affinity and low background based on CN and amphipathic regulatory strategies and in vivo imaging of AD mice. Talanta, 2025, 281, 126858.
9. Cuizhen Lu#, Liang Xu#, Yu Jiang#, Caiqiang Liao, Yixin Li, Yinghao Tang, Zhongyong Xu, Xinfeng Du, Taoyuze Lv, Yalong Wang*, Tianyi Qin*, Bin Liu, Mingqiang Zhu. Sensitive and accurate monitoring of urinary albumin and point-of-care testing using a fluorescent probe with anti-interference capacity against exogenous drugs. Talanta, 2024, 279, 126575
10. Wenda Zhang, Xijian Duan, Yangzhi Tan, Junjie Hao, Hongmei Zhu, Qingqian Wang, Hongcheng Yang, Haochen Liu, Kai Wang, Zhiwen Wang, Ya-Long Wang*, Yujie Song*, and Xiao Wei Sun*. Giant Pyramidal Near-Infrared InP/ZnS Quantum Dots with Size Over 15 nm for Cell Imaging. Laser Photonics Reviews, 2024, 2400367
11. Zhaohui Wang#,*, Min Dong#, Yuhang Pan, Lu Zhang, Haozhuo Lei, Yuanzhe Zheng, Yanbin Shi, Shuang Liu, Nan Li*, Yalong Wang*. Turning Threat to Therapy: A Nanozyme-Patch in Surgical Bed for Convenient Tumor Vaccination by Sustained In Situ Catalysis. Advanced Healthcare Materials, 2024, 2304384
12. Cui-Zhen Lu#, Cai-Yun Wang#, Chao Song#, Tianyi Qin*, Taoyuze Lv, Conghui Zeng, Shihong Chen, Zhongyong Xu, Zhiqing Xun*, Bin Liu*, Ya-Long Wang*, and Ming-Qiang Zhu. A ratiometric fluorescent indicator-displacement assay for on-site determination and intracellular imaging of nitroxinil. Food Chemistry, 2024, 435(1), 137617
13. Ya-Long Wang#, Ting Luo#, Jianping Zhang#, Cheng Fan, Xiangning Li, Chong Li*, Hui Gong, Qingming Luo*, Ming-Qiang Zhu*. AIE-based fluorescent micro-optical sectioning tomography for automatic 3D mapping of β-amyloid plaques in Tg mouse whole brain. Chemical Engineering Journal, 2022, 446, 136840
14. Cheng Fan#, Ze-Qiang Chen#, Chong Li*, Ya-Long Wang*, Qi Yu, Ming-Qiang Zhu*. Hydrophilic AIE-Active Tetraarylethenes for Fluorescence Sensing and Super-Resolution Imaging of Amyloid Fibrils from Hen Egg White Lysozyme. ACS Applied Materials & Interfaces, 2021, 13(17), 19625–19632
15. Ya-Long Wang#, Chong Li#*, Hong-Qing Qu, Cheng Fan, Peng-Ju Zhao, Rui Tian, Ming-Qiang Zhu*. Real-Time Fluorescence In Situ Visualization of Latent Fingerprints Exceeding Level 3 Details Based on Aggregation-Induced Emission. Journal of the American Chemical Society, 2020, 142(16), 7497–7505
授权专利：
1. 一种标记Aβ斑块的蓝色水溶性探针及其制备方法和应用. 王亚龙, 张振宇, 李泽君, 秦天依, 朱明强. ZL 2025103204333
2. 一种负载光敏剂和表皮生长因子的水凝胶纳米材料及其制备方法. 朱明强，王舰，王亚龙，陈权. ZL 2024113407518.
3. 一种用于膨胀显微镜成像的水凝胶及其制备方法和样品膨胀处理方法. 朱明强, 张露, 王亚龙, 唐玉娇, 王舰. ZL 2024115008438.
4. 一种标记Aβ斑块的水溶性探针及其制备方法和应用. 王亚龙, 朱明强, 侯婷婷. 中国. 发明专利. ZL 202210495597.6
5. 一种水溶性红色荧光的线粒体靶向探针及应用. 李冲，田蕊，朱明强，王亚龙. 中国. 发明专利. ZL 202011009611.4
6. 一种超分子聚合物水凝胶、其制备和应用. 朱明强, 赵鹏举, 李冲, 王亚龙. 中国. 发明专利. ZL 201910976144.3.
7. 一种聚集诱导荧光探针在指纹荧光成像中的应用. 李冲，田蕊，朱明强，王亚龙. 中国. 发明专利. ZL 201910983505.7
8. 一种线型聚集诱导发光探针及其制备方法与应用. 朱明强, 王亚龙, 李冲, 范成. 中国. 发明专利. ZL 201810326261.0
9. 一种水溶性聚集诱导发光探针及其制备方法与应用. 朱明强, 王亚龙, 李冲, 余琦. 中国. 发明专利. ZL201811222518.4
科研项目：
1. 国家自然科学基金，面上项目（2267050072），2027.01-2030.12，50万元，在研，主持。
2. 国家自然科学基金，地区科学项目（3266100002），2027.01-2030.12，32万元，在研，主持。
3. 海南省科技厅，重点研发项目（ZDYF2026SHFZ034），2026.03-2029.03，89万元，在研，主持。
4. 国家自然科学基金，地区科学基金（22165008），2022.01-2025.12，35万元，结题，主持。
5. 海南省自然科学基金，高层次人才项目（521RC506），2021.09.29至2024.06.30，8万元，结题，主持。
