张应军（博士），海南大学生物医学工程学院讲师。2016年本科毕业于湖北大学物理学专业，2021年博士毕业于华中科技大学国家脉冲强磁场科学中心光学专业，2021年七月入职海南大学。主要研究方向为超（高）分辨光学显微成像技术，已在Nano Letters, ACS Photonics, Nanoscale, Optics Express等期刊发表论文20余篇，主持海南省重点研发项目一项，担任Optics Express等期刊审稿人。
主要研究方向：
生物研究与临床诊断所面临的前沿超（高）分辨光学显微成像技术
1） 免切片病理成像技术；
2） 自动化高通量单分子定位成像技术；
3） 显微多光谱成像技术。
代表论文：
1. Yulong Sun, Xingguang Chen, Xiaoyang Tang, Yingqi Sun, Bing Shi, Zhen-Li Huang, and Yingjun Zhang*, Dual-color Single-molecule Localization Microscopy with Sub-nanometer Channel Misalignment and Sub-1% Color Crosstalk. Optics Express, (In production).
2. Xiaoguang Guo, Xingguang Chen, Yaolong Li, Yan Wu, Fanhao Qiu, Zhengxia Wang, Yingjun Zhang*, and Zhen-Li Huang*, Slide-Free Histopathology via Fluorescent Layer-Adaptive Subcellular Imaging for Less Artifacts and Faster Intraoperative Diagnosis. ACS Photonics 2026, 13 (7): 1790-1800.
3. Yaolong Li, Weibing Kuang, Zhengxia Wang, Yingjun Zhang*, and Zhen-Li Huang*, CC-DenseSTORM: deep learning enables colorimetry camera-based simultaneous two-color single-molecule localization microscopy with dense emitters. Biomedical Optics Express 2026, 17 (3): 1319-1334.
4. Qihang Song, Qihuan Li, Dongjian Cao, Lin Cai, Wanchen Wu, Jie Yang, Yingjun Zhang*, and Zhen-Li Huang*, Marker-free drift correction for 3D RNA imaging via spatiotemporal clustering and imputation. Optics Express 2025, 33 (19): 39452-39466.
5. Lin Cai, Qihang Song, Dongjian Cao, Qihuan Li, Wancheng Wu, Yinghao Xiao, Xingguang Chen, Shujing Huang, Jie Yang*, Yingjun Zhang*, and Zhen-Li Huang*, Tilted thick light-sheet microscopy with context-aware 3D localization for RNA imaging in intact 50 μm-thick sections. Optics Express 2025, 33 (15): 32850-32861.
6. Caiwei Li, Kehan Liu, Xiaoguang Guo, Yinghao Xiao, Yingjun Zhang*, and Zhen-Li Huang*, Robust autofocus method based on patterned active illumination and image cross-correlation analysis. Biomedical Optics Express 2024, 15 (4): 2697-2707.
7. Wenping Hu, Yingjun Zhang*, and Weihang Zhou*, Nanometer-precision measurements of geometric fluctuations via momentum-filtered spectroscopy. Applied Physics Express 2024, 17 (7): 072003.
8. Shuhao Guo, Jiaxun Lin, Yingjun Zhang*, and Zhen-Li Huang, Enhancing the data processing speed of a deep-learning-based three-dimensional single molecule localization algorithm (FD-DeepLoc) with a combination of feature compression and pipeline programming. Journal of Innovative Optical Health Sciences 2024, 18 (02): 2450025.
9. Liqing Zhu, Yichun Pan, Linqi Chen, Zheng Wang, Fangxin Zhang, Guangran Yang, Changchang Huang, Wenping Hu, Long Zhang, Yingjun Zhang*, Hongxing Dong*, and Weihang Zhou*, Rydberg State Single-Mode Polariton Lasing with Ultralow Threshold via Symmetry Engineering. Nano Letters 2023, 23 (17): 7797-7804.
10. Cheng Wu, Weibing Kuang, Zhiwei Zhou, Yingjun Zhang*, and Zhen-Li Huang, FACAM: A Fast and Accurate Clustering Analysis Method for Protein Complex Quantification in Single Molecule Localization Microscopy. Photonics 2023, 10 (4): 427.
11. Mengting Li, Qihang Song, Yinghao Xiao, Junnan Wu, Weibing Kuang, Yingjun Zhang*, and Zhen-Li Huang*, LuckyProfiler: an ImageJ plug-in capable of quantifying FWHM resolution easily and effectively for super-resolution images. Biomedical Optics Express 2022, 13 (8): 4310-4325.
12. Mengting Li, Mingtao Shang, Luchang Li, Yina Wang, Qihang Song, Zhiwei Zhou, Weibing Kuang, Yingjun Zhang*, and Zhen-Li Huang*, Real-time image resolution measurement for single molecule localization microscopy. Optics Express 2022, 30 (15): 28079-28090.
13. Xinhan Zhang#, Yingjun Zhang#, Hongxing Dong, Bing Tang, Dehui Li, Chuan Tian, Chunyan Xu, and Weihang Zhou*, Room temperature exciton–polariton condensate in an optically-controlled trap, Nanoscale 2019, 11 (10): 4496-4502.
14. Yingjun Zhang, Xinhan Zhang, Bing Tang, Chuan Tian, Chunyan Xu, Hongxing Dong, and Weihang Zhou*, Realization of an all-optically controlled dynamic superlattice for exciton–polaritons, Nanoscale 2018, 10 (29): 14082-14089.
15. Yingjun Zhang, Hongxing Dong, Xinhan Zhang, Bing Tang, Chuan Tian, Chunyan Xu, and Weihang Zhou*, Fabry-Perot type polariton modes and their dynamics revealed by Young's interference experiment, Optics Express 2018, 26 (14): 18214-18221.
16. Yingjun Zhang, Xinhan Zhang, Bing Tang, Chuan Tian, Chunyan Xu, Hongxing Dong, and Weihang Zhou*, Resolving lifetimes of degenerate polariton states in an optical superlattice, Applied Physics Express 2018, 11 (8): 082003.
主持科研项目：
1. 海南省重点研发项目，ZDYF2022SHFZ126，基于暗场照明方式的厚样本全景显微成像技术研究，202203至 2024-03，结题， 主持
发明专利：
1. 黄振立, 韦福秀, 张应军, 孙英旗, 吴艳, 孙玉龙, 一种超分辨成像系统及生物标志物的检测方法, 2025-12-05, CN202411801780.X (已授权)
2. 张应军, 陈星光, 黄振立, 基于空间错位通光转轮的同时多色成像系统, 2025-10-24,CN202511529072.X (已公开)
3. 张应军, 黄振立, 李才伟, 孙玉龙, 吴晚辰, 基于固定光斑图像的自动对焦方法、系统、设备及介质, 2024-07-15, CN202410944670.2 (已公开)
学生获奖情况：
1. 海南省研究生创新科研课题，2021级硕士；
2. 海南大学研究生优秀毕业论文，2021级硕士。
招生需求:
光学、光学工程、生物医学工程、电子信息工程专业等相关硕士生2-3人
联系方式：yjzhang@hainanu.edu.cn
