周欣，海南大学生物医学工程学院客座教授，中国科学院精密测量科学与技术创新研究院研究员，博导，院长。基金委创新研究群体项目负责人，国家杰出科学青年基金、国家重大科研仪器设备研制专项（部委推荐）和国家重点研发计划首席科学家。现任国家自然科学基金委员会医学科学部第六届专家咨询委员会委员，国际华人医学磁共振学会主席，中国化学会理事，中国生物物理学会分子影像学专委会副主任委员。获2023年度国家技术发明奖二等奖（第一完成人）、湖北省科技奖一等奖（2次）、全国创新争先奖、首届科学探索奖、CCTV 2018年度全国十大科技创新人物、“王天眷波谱学奖”等荣誉。
主要从事医学影像与生物医学工程的新仪器、新技术及新应用研究，在我国率先开展多核（多种原子核）磁共振成像（MRI）临床研究。自主研制的创新医疗器械--人体肺部多核磁共振成像装备获国家药品监督管理局批准上市，是当前全球首台获批的可用于气体成像的临床多核磁共振成像装备。成功“点亮”肺部，解决传统MRI对肺部空腔无法清晰成像的难题，在全国多家三甲医院开展了慢阻肺、肿瘤、新冠肺炎等肺部重大疾病的临床应用。发展了多核和人工智能的MRI新技术，为肺部和脑部等重大疾病和肿瘤的早期检测提供新的医学影像手段与策略。发表SCI论文220余篇，授权国内外发明专利170余件。
招生需求：
招收物理、化学、生物医学工程及相关专业的硕士生和博士生2-3人，博士后2人。
联系方式：xinzhou@wipm.ac.cn
荣誉与奖励：
2023 国家技术发明奖二等奖
2023 朱良漪分析仪器创新成果奖
2021 中国科学院年度创新人物
2020 全国创新争先奖
2019 首届科学探索奖
2019 “国家高层次人才特殊支持计划”科技创新人才
2018 CCTV 2018年度全国十大科技创新人物
2016 中国科学院青年科学家奖
代表性论著：
1 Qingbin Zeng#, Quer Yue#, Ming Zhang, Rui Zhou, Zhen Wang, Zhongyu Xiao, Yaping Yuan, Xiuchao Zhao, Weiping Jiang, Lei Zhang, Yuqi Yang, Minghui Yang, Haidong Li, Louis-S. Bouchard, Qianni Guo*, Xin Zhou*. Multivariate Metal-Organic Frameworks Enable Chemical Shift-Encoded MRI with Femtomolar Sensitivity for Biological Systems. Nature Communications, Vol 16, 6832. (2025).
2 Hongchuang Li#, Haidong Li#, Li Fan#，Ming Zhang, Xiaoling Liu, Xiuchao Zhao, Yeqing Han, Yang Jin, Louis-S. Bouchard, Shiyuan Liu, Xin Zhou*. Dynamic Ventilation Functional MRI of the Lung with Sub-millimeter Spatial Resolution and Millisecond Temporal Resolution. Science Bulletin, Vol 70(24), 4142-4145. (2025).
3 Yuqi Yang#, Sen Yue#, Luyang Shen#, Huiling Dong, Haidong Li, Xiuchao Zhao, Qianni Guo, Xin Zhou*. Ultrasensitive 129Xe Magnetic Resonance Imaging: From Clinical Monitoring to Molecular Sensing. Advanced Science, Vol 12(8), 2413426. (2025).
4 Ming Zhang#, Haidong Li#, Yi Xiao#, Hongchuang Li, Xiaoling Liu, Xiuchao Zhao, Yu Zheng, Yeqing Han, Fumin Guo, Xianping Sun, Jianping Zhao, Shiyuan Liu*, Xin Zhou*. Assessment of Global and Regional Lung Compliance in Pulmonary Fibrosis With Hyperpolarized Gas MRI. Journal of Magnetic Resonance Imaging, Vol 61(3), 1404-1415. (2025).
5 Haidong Li#, Hongchuang Li#, Ming Zhang#, Chaolin Huang, Xin Zhou*. Direct Imaging of Pulmonary Gas Exchange with Hyperpolarized Xenon MRI. The Innovation, Vol 5(6), 100720. (2024)
6 Yuan Fang#, Haidong Li#, Luyang Shen, Ming Zhang, Ming Luo, Hongchuang Li, Qiuchen Rao, Qi Chen, Yecheng Li, Zimeng Li, Xiuchao Zhao, Lei Shi, Qian Zhou, Yeqing Han, Fumin Guo, Xin Zhou*. Rapid Pulmonary 129Xe Ventilation MRI of Discharged COVID-19 Patients with Zigzag Sampling. Magnetic Resonance in Medicine, Vol 92(3), 956-966. (2024).
7 Zimeng Li#, Sa Xiao#, Cheng Wang, Haidong Li, Xiuchao Zhao, Caohui Duan, Qian Zhou, Qiuchen Rao, Yuan Fang, Junshuai Xie, Lei Shi, Fumin Guo, Chaohui Ye, Xin Zhou*. Encoding Enhanced Complex CNN for Accurate and Highly Accelerated MRI. IEEE Transactions on Medical Imaging, Vol 43(5), 1828-1840. (2024).
8 Qiuchen Rao#, Haidong Li#, Qian Zhou#, Ming Zhang, Xiuchao Zhao, Lei Shi, Junshuai Xie, Li Fan, Yeqing Han, Fumin Guo, Shiyuan Liu, Xin Zhou*. Assessment of Pulmonary Physiological Changes Caused by Aging, Cigarette Smoking, and COPD with Hyperpolarized 129Xe Magnetic Resonance. European Radiology, Vol 34, 7450-7459. (2024).
9 Ming Zhang#, Haidong Li#, Hongchuang Li, Xiuchao Zhao, Xiaoling Liu, Yeqing Han, Xianping Sun, Chaohui Ye, Xin Zhou*. Dynamic Evaluation of Acute Lung Injury Using Hyperpolarized 129Xe Magnetic Resonance. NMR in Biomedicine, Vol 37(4), e5078. (2024).
10 Zimeng Li#, Sa Xiao#, Cheng Wang, Haidong Li, Xiuchao Zhao, Qian Zhou, Qiuchen Rao, Yuan Fang, Junshuai Xie, Lei Shi, Chaohui Ye,Xin Zhou*. Complementation-Reinforced Network for Integrated Reconstruction and Segmentation of Pulmonary Gas MRI with High Acceleration. Medical Physics, Vol 51(1), 378-393. (2024).
11 Chenlu Yuan#, Qianni Guo*#, Qingbin Zeng, Yaping Yuan, Weiping Jiang, Yuqi Yang, Louis-S. Bouchard, Chaohui Ye, Xin Zhou*. Dual-Signal Chemical Exchange Saturation Transfer (Dusi-CEST): An Efficient Strategy for Visualizing Drug Delivery Monitoring in Living Cells.Analytical Chemistry, Vol 96(4), 1436-1443. (2024).
12 Xu Zhang#, Yuqi Yang#, Yaping Yuan, Sen Yue, Xiuchao Zhao, Quer Yue, Qingbin Zeng, Qianni Guo, Xin Zhou*. Hyperpolarized 129Xe Atoms Sense the Presence of Drug Molecules in Nanohosts Revealed by Magnetic Resonance Imaging. Analytical Chemistry. (2024).
13 Yuqi Yang#, Baolong Wang#, Xu Zhang, Hongchuang Li, Sen Yue, Yifan Zhang, Yunhuang Yang, Maili Liu, Chaohui Ye, Peng Huang*, Xin Zhou*. Activatable Graphene Quantum-Dot-Based Nanotransformers for Long-Period Tumor Imaging and Repeated Photodynamic Therapy. Advanced Materials, Vol 35(23), 2211337. (2023).
14 Qian Zhou#, Haidong Li#, Qiuchen Rao#, Ming Zhang, Xiuchao Zhao, Luyang Shen, Yuan Fang, Hongchuang Li, Xiaoling Liu, Sa Xiao, Lei Shi, Yeqing Han, Chaohui Ye, Xin Zhou*. Assessment of Pulmonary Morphometry using Hyperpolarized 129Xe Diffusion-Weighted MRI with Variable-Sampling-Ratio Compressed Sensing Patterns. Medical Physics, Vol 50(2), 867-878. (2023).
15 Cheng Wang#, Lu Huang#, Sa Xiao#, Zimeng Li, Chaohui Ye, Liming Xia*, Xin Zhou*. Early Prediction of Lung Lesion Progression in COVID-19 Patients with Extended CT Ventilation Imaging. European Journal of Nuclear Medicine and Molecular Imaging, Vol 48, 4339-4349. (2021).
16 Qian Zhou#, Qiuchen Rao#, Haidong Li, Ming Zhang, Xiuchao Zhao, Lei Shi, Chaohui Ye, Xin Zhou*. Evaluation of Injuries Caused by Coronavirus Disease 2019 Using Multi-Nuclei Magnetic Resonance Imaging. Magnetic Resonance Letters, Vol 1(1), 2-10. (2021).
17 Weiping Jiang#, Qianni Guo#, Qing Luo, Xiaoxiao Zhang, Yaping Yuan, Haidong Li, Xin Zhou*. Molecular Concentration Determination Using Long-Interval Chemical Exchange Inversion Transfer (CEIT) NMR Spectroscopy. The Journal of Physical Chemistry Letters, Vol 12, 8652-8657. (2021).
18 Qingbin Zeng#, Binglin Bie#, Qianni Guo*, Yaping Yuan, Qi Han, Xiaocang Han, Mingwei Chen, Xu Zhang, Yunhuang Yang, Maili Liu, Pan Liu, Hexiang Deng*, Xin Zhou*. Hyperpolarized Xe NMR Signal Advancement by Metal-Organic Framework Entrapment in Aqueous Solution. PNAS, Vol 117(30), 17558-17563. (2020).
19 Sa Xiao#, He Deng#, Caohui Duan, Junshuai Xie, Haidong Li, Xianping Sun, Chaohui Ye, Xin Zhou*. Highly and Adaptively Undersampling Pattern for Pulmonary Hyperpolarized 129Xe Dynamic MRI. IEEE Transactions on Medical Imaging, Vol 38(5), 1240-1250. (2019).
20 Haidong Li#, Zhiying Zhang#, Jianping Zhong, Weiwei Ruan, Yeqing Han, Xianping Sun, Chaohui Ye, Xin Zhou*. Oxygen-Dependent Hyperpolarized 129Xe Brain MR. NMR in Biomedicine, Vol 29(3), 220-225. (2016).
21 Haidong Li, Zhiying Zhang, Xiuchao Zhao, Xianping Sun, Chaohui Ye, Xin Zhou*. Quantitative Evaluation of Radiation-Induced Lung Injury with Hyperpolarized Xenon Magnetic Resonance. Magnetic Resonance in Medicine, Vol 76(2), 408-416. (2016).
22 叶朝辉*，骆清铭*，周欣*. 影像揭示生命奥秘. 中国科学：生命科学，Vol 50(11), 1155-1157. (2020).
专利：
1. Xin Zhou; Yeqing Han; Xianping Sun; Lei Shi; Maili Liu; Chaohui Ye; Device Having Inert Gas Nucleus Channel and Method for Magnetic Resonance Imaging Using the Same, 2022-10-19, 欧洲, EP3422036B1.
2. Xin Zhou; Xianping Sun; Xiuchao Zhao; Maili Liu; Chaohui Ye; Optical-Fiber Atomic Light-Filtering Apparatus, 2020-10-6, 美国, US10795171B2.
3. 周欣；袁亚平；郭茜旎；孙献平；叶朝辉；使用绝热射频脉冲测量射频B1场分布的磁共振成像方法，2020-8-11，中国，ZL201911151143.1。
4. 周欣；谢军帅；石磊；孙献平；叶朝辉；一种基于降升频的磁共振成像方法，2019-10-25，中国，ZL201810906189.9。
5. 周欣；肖洒；邓鹤；孙献平；叶朝辉；一种基于变采样率的肺部超极化气体动态成像方法，2018-12-25，中国，ZL201610743164.2。
主持科研项目：
1 国家自然科学基金委员会，专项项目，82441015，多源异构数据驱动的COPD跨模态智能诊疗策略研究（联合申请A），2025-01至2027-12，在研，主持
2 国家自然科学基金委员会，国家重大科研仪器研制项目（自由申请），82127802，脑部多核超灵敏MRI仪器研制，2022-01至2026-12，在研，主持
3 国家自然科学基金委员会，创新研究群体项目，21921004，生命波谱与成像，2020-01至2024-12，已结题，主持
4 科学技术部，国家重点研发计划，2018YFA0704000，肺癌的超高灵敏谱学与成像新技术研究，2019-01至2024-08，已结题，主持
5 国家自然科学基金委员会，国家杰出青年科学基金，81625011，超灵敏磁共振成像，2017-01至2021-12，已结题，主持
6 国家自然科学基金委员会，国家重大科研仪器设备研制专项（部委推荐），81227902，用于人体肺部重大疾病研究的磁共振成像仪器系统研制，2013-01至2017-12，已结题
